Any enemies in the vicinity, I gotta mack up

from Tech N9ne (Ft. Busta Rhymes, Ceza, D-Loc, JL B.Hood, Twista, Twisted Insane, U$O & Yelawolf) – Worldwide Choppers Lyrics on Rap Genius

Meaning

He means that he’ll beat them no matter what.
Mack : A mack can be a person who is smooth, slick, the Best of the Best, a Pimp, a Ladies Man, the guy who runs everything a.k.a. the Boss. A mack is a person who is always flirting and hitting on girls. Almost always successful at it too.

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