Booyaka booyaka, we bring it straight to ya
From 22's to Luger's the shit that shoot through ya

from Snoop Dogg (Ft. Butch Cassidy, Dr. Dre, Goldie Loc, Master P, Nate Dogg & Tray Deee) – Lay Low Lyrics on Rap Genius

Meaning

We deal in a variety of firearms.

“22’s” referring to some 22 caliber gun, most probably a pistol.

“Luger”:

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