On the uptown A, nigga you know what’s up or don’t you
from Azealia Banks – 212 Lyrics 5 on Rap Genius
Meaning
Take the A to Harlem—where she’s from.
http://www.youtube.com/watch?v=hRGFqSkNjHk
“You know what’s up, or don’t you?” or “You know what’s Upper, don’t you?” is a sort of sneering rhetorical question directed at a non-native Manhattanite who might get confused about what’s technically considered the “Upper” part of Manhattan, something a native of the 212 would be savvy to.
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