Just blew trial, crack lobsters Little Italy
Your wife she a screamer yellin' slow down Joe, you killin' me
Beat her like a prize fight mommy I’m a rude boy

from DJ Khaled (Ft. Busta Rhymes, Diddy, Fabolous, Fat Joe, Jadakiss, Nicki Minaj, Rick Ross, Swizz Beatz & T-Pain) – All I Do Is Win (Remix) Lyrics on Rap Genius

Meaning

Fat Joe is “killing” the wife while “doing” her. I don’t know why but this might be a reference to his weight

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