Do you even remember what the issue is?
You just trying to find where the tissue is

from Kanye West – I Wonder Lyrics on Rap Genius

Meaning

The girl wants to make a problem out of everything and to get attention from ‘Ye, but the problem actually doesn’t exist or is long since past. She’s trying to cut deep, or hurt him, when the origin of the fight is long forgotten.

It is also stylistically important to note that up to this point in the song, Kanye had been enunciating and stressing the syllables in each word. Here, he switches it up to a quicker, more frantic flow: in turn stressing how aggravated he is with women who try to demonize good men to garner sympathy for themselves.

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