As I begin to bust
On the wick-wack, fucked up suckers ya can't trust

from Dr. Dre (Ft. Kurupt, The Lady of Rage & RBX) – Lyrical Gangbang Lyrics on Rap Genius

Meaning

… Pulls out her heater and starts blasting off at untrustworthy motherfuckers!

Wick-Wack is probably a reference to a certain line in “My Philosophy” by Boogie Down Productions

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