Socks soaking wet, I been running y'all
I reload every hundred yards, I'm comin' forward, you better know me

from Lil Wayne (Ft. Robin Thicke) – Shooter Lyrics on Rap Genius

Meaning

In this last verse, Wayne stops addressing the Southern Hip Hop criticism and instead picks up on the story of the bank-robbers that Robin has been telling so far.

After alerting the police in the previous lines, Wayne is now running from the police; getting his socks sweaty and reloading his gun as he runs to fire back.

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