Like a sprained ankle, boy I ain't nothing to play with

from Drake (Ft. Eminem, Kanye West & Lil Wayne) – Forever Lyrics on Rap Genius

Meaning

You shouldn’t play basketball with a sprained ankle, and you shouldn’t “play” (try to mess) with Drake

A noted bit of irony is that before this song was released, Drake hurt his knee in a game of basketball, then further injured it on stage; after this, he had to get surgery.

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