Coming down with the 5th in the back

from DJ Screw (Ft. Big Moe, Big Pokey, Bird, D-Mo, Haircut Joe, Key-C, K-Luv & Yungstar) – June 27th Freestyle Lyrics on Rap Genius

Meaning

D-Mo’s got his Glock four-fifth (.45 mm) in the trunk of his Cadillac.

He could also be referencing the 5th wheel (spare with a 84 Cadillac rim)

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