Okay respect is in the heart so that's where I'mma start

from Lil Wayne – Dr. Carter Lyrics on Rap Genius

Meaning

Once Wayne fixes respect, the core of the hiphop ethos, he can rebuild the confidence, vocab, and metaphors. Respecting the game is as vital as the heart, pumping good vibes into all other facets of rap. To Wayne, this is pivotal.

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