Most of the clean faces be the most dirty

from Kid Cudi – Soundtrack 2 My Life Lyrics on Rap Genius

Meaning

The people who seem the most polished and caring are the ones that will stab you in the back first.

This line probably specifically refers to women due to the line above and two lines below referring to women.

Kid Cudi is saying that a lot of the girls that appear to be “wife material” for settling down actually tend to turn out to be the wrong type of woman, and wouldn’t be suitable for settling down with. This makes it difficult for Cudi to find the right girl for said settling down.

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