They got they mind on they money, money on they mind
They got they finger on the trigger, hand on the nines

from Wyclef Jean (Ft. Akon, Lil Wayne & Niia) – Sweetest Girl Lyrics on Rap Genius

Meaning

This pays homage to a 2Pac line from MC Breed’s “Gotta Get Mine”.

“I keep my mind on my money, money on my mind
Finger on the trigger, nigga, hand on my nine”

This speaks to the pressures that come with gaining and maintaining money and power. If you want to rise up in the world, you have to always be aware of your surroundings and prepared for something to go wrong. This includes keeping a “9” (9mm gun) on you at all times.

Snoop Dogg references this same line on “Gin and Juice”

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