Friends become rats, I'm talkin Judas in expensive slacks

from Macklemore and Ryan Lewis (Ft. Arcade Fire, Buffalo Madonna & Champagne Champagne) – Kings Lyrics on Rap Genius

Meaning

He is saying that friends are most likely the ones to turn on you and become a “rat”. Jesus was betrayed by his disciple, Judas, who took pay to turn him in. He compares modern-day “rats” to a Judas in expensive, modern slacks, as his friends would be wearing.

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