I run the world take your hood to the gym
Stretch it all out, get it all thin

from Game (Ft. Lupe Fiasco) – Skate On Lyrics on Rap Genius

By saying “I run the world”, Lupe is saying that he is ruling the world. However, the primary meaning of “run” is to move quickly, which we usually do when we are exercising. This ties in with the gym part i.e. the most common place to exercise in, and Lupe uses personification to say that he makes your hood exercise.

Exercising is good for your health, so this line is a metaphor to say that Lupe is making our hoods a better place to live in.

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