Young or old, there ain’t no comparin' me
I just cleared that up, moment of clarity

from Lil Wayne – D.O.A. Lyrics on Rap Genius

Meaning

“Moment of Clarity” is a Jay-Z song off of The Black Album

Jay and Wayne are both Carters, young and old(er), age wise and game wise hence the “young or old”

Wayne is implicitly saying he’s better than Jay-Z which is the first time that he’s straight-up claiming to be better; Wayne calls himself the best rapper alive, but previously it had been with the caveat that Jay-Z was in a different category (on “Bring it Back” he says “Uhh, the best rapper alive / Since the best rapper retired” — since Wayne’s The Carter was released a year after Jay-Z “retired” after The Black Album)

In the original version of “D.O.A” Jay-Z finishes the first verse off with:

this is death of auto tune: moment of silence

Wayne appears to be competing with and mocking Jay’s ending

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