All that talking is gon' give me a Tylenol
Tylenol is the most well-known brand of over-the-counter pain medication. He’s getting a headache from hearing this woman’s voice.
It’s also an example of of Synecdoche, bitches — using the ‘Tylenol’ to refer to the headache, a part to refer to the whole.
To help improve the meaning of these lyrics, visit "Celebration" by Kanye West Lyrics and leave a comment on the lyrics box