If you really wanna fuck with me, I'm ready
Baby, let me give you a call
How long will it take to break you off?

from 2Pac – What'z Ya Phone # Lyrics on Rap Genius

Meaning

2Pac wants to make a girl horny with telephone sex. He is sure that she will get an orgasm, and therefore only asks how many minutes it might take.

‘breaking her off’ means giving her an orgasm.

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