Yes I do sir, what am I on? You sir, are on truth serum

from Eminem – Big Weenie Lyrics on Rap Genius

Meaning

Drugs are like a truth serum for some (get me high enough and I’ll tell you what you wanna know!)
Eminem again brings out the difference between rapping in vain — like Benzino — versus rapping the truth — as Eminem himself does.

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