Half the patients wasted self prior to Commencement

from Aesop Rock – 9-5'ers Anthem Lyrics on Rap Genius

Meaning

People enter the workforce, sell out, or make some other life mistake before graduating.

“Wasted self” might be a reference to either burning out, or suicide (to “waste”, i.e. kill).

Also, “Commencement” might be a sly reference to his song “Commencement At The Obedience Academy”

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