One more time

from The Notorious B.I.G. – What's Beef? Lyrics on Rap Genius

This came off to me from the bat as a double entendre:

.He says this because he is repeating the hook, I believe, as most emcees do in the background.

.The second interpretation is clearly a shot at California emcee Tupac and with this he says he is going to put him in the intensive care unit- yet again, for it is said that he had a surprise hit carried out on him.

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