Look, if you had, one shot
Or one opportunity
To seize everything you ever wanted
In one moment
Would you capture it, or just let it slip?

from Eminem – Lose Yourself Lyrics on Rap Genius

Meaning

Most likely the lines Eminem will be best remembered for, lines that have been played in countless high school, college, and professional stadiums across the nation. This intro summarizes what the entire song is about: either seizing your one chance of success when it comes by, or regretting not doing so for the rest of your life.

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