I changed up my old ways, to kill 'em like OJ

from Hit-Boy – Jay-Z Interview Lyrics on Rap Genius

Meaning

OJ Simpson was a very well liked NFL star until he was accused of killing his ex-wife and her friend. Although, he was found innocent, many believe he still committed the crime.

Hit-Boy switched his lifestyle up to pursue a career in producing so he could dominate (“kill”) his enemies.

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