Mom told me that I need to grow up
I was in the room trying to blow up
Q’s mom didn’t believe that he could make it in the music business, emphasizing that he needed to grow up & get over himself and these dreams he had. He never did listen to his mom and he was still in his room dropping bars trying to blow up, and who would have thought that in the end, it worked out.
Blow up could also refer to weed has it does in the next line. Coincidentally, a year after this verse, Q admits he does smoke weed with his mother:
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