I started smoking dust and been insane since

from Big L (Ft. Jay Z) – Seven-Minute Freestyle Lyrics on Rap Genius

Meaning

“Dust” is Angel Dust/PCP. In the ‘90’s was when PCP use was most prominent. Use of “dust” can cause hallucinations, aggression or suicidal behavior. Big L’s use of the drug may have had more negative effects than positive.

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