Like all my niggas suffer from pain, start cuttin' the 'caine, feels good to switch your guts into BRAINS. YEAH!

from Styles P – Reminisce Lyrics on Rap Genius

Meaning

Styles P mainly raps for men who’re currently involved in the criminal underworld, he himself has stated this numerous times.
This line is a prime example:
“Like all my niggas suffer from pain” < Many of his homies suffer from moderate, to severe depression either from past child-hood experiences, or the result of the lifestyle they live. Maybe even a combination of both.

“Cuttin the caine” < They’re distributing cocaine at retail, so they’re chopping down the quality by adding other products ranging from baby powder and crushed glass, to other drugs like quinine and B12. This is done so they can make more off of what they originally got the cocaine for. Most cocaine retailers just convert it into crack.

“Feels good to switch your guts into brains” < If you have guts (courage), he’s going to turn them into brains! (kill you)

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