Picture working so hard, and you can't cut through
That can mess up your whole life, like an uncle that touched you

from Kanye West (Ft. Ghostface Killah & Pusha T) – New God Flow Lyrics on Rap Genius

Meaning

In Kanye’s eyes, the pain of struggling and working hard for success your entire life and failing to achieve anything is just as damaging as the psychological damage that befalls victims of child molestation. I’m not sure that I agree with Kanye on this comparison — hurting kids is a special, horrible kind of evil and deserves a special Hell unto itself

Since Kanye specifically cited an uncle as the perpetrator, we have to bring up the (then) recent case of former Penn State assistant football coach Jerry Sandusky, who was charged with and found guilty of child molestation (something he’d been doing for decades); one of the victims was his own nephew, who stated in court that the abuse changed his life forever.

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