If a nigga step on my white Air Ones
It's red rum,

from Game (Ft. 50 Cent) – How We Do Lyrics on Rap Genius

Meaning

“Air Ones”=fancy Nike kicks
“red rum”=murder, a bit of wordplay popularized by Stephen King (read it backwards)

Game’s threat reflects a depressing truth about urban communities where people can be, and have been, killed over shoes.

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