I got 99 problems, being a bitch ain't one, hit me
Throughout this whole song, Jay takes care of the three types of bitches plaguing him: critics, cops (drug sniffing dogs), and weak men. After overcoming all these obstacles, Jay feels enough confidence to ask anyone around to try and hit him, or instigate him.
He can now move on to more pertinent, exciting endeavors.
To help improve the meaning of these lyrics, visit "99 Problems" by Jay Z Lyrics and leave a comment on the lyrics box