The doctor said I had blood clots, but I ain't Jamaican, man

from Kanye West – Through The Wire Lyrics on Rap Genius

Bloodclot is a versatile Jamaican insult. The closest comparison would be fuck/fucking/motherfucking/etc. Also, Biggie was of Jamaican descent.

Running off the previous bar, ‘Ye is referencing Biggie’s oft quoted line from his posthumous Life After Death.

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