Ayyo Biggie Put your hands up

from 2Pac (Ft. Outlawz) – Fuck Em All Lyrics on Rap Genius

Meaning

Taking a common saying from the police, “Put your hands where I can see them.”, and fits it to belittle his rival Biggie Smalls. He’s cornered Biggie and asks him to surrender and bow down to his greatness, and he probably imagined a gun pointed at him.

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