I ain't giving nobody shit, I'mma show them
I gave Game hits, he told me to suck dick
Started screaming Westside and Dre ain't say shit

from 50 Cent – So Disrespectful Lyrics on Rap Genius

Meaning

He doesn’t want to assist anyone due to past experiences, for example Game.

Even though 50 Cent and Game were in a public feud, 50 was still featured on Game’s debut album “The Documentary” three times. Game’s response to the crucial 50 features was a

50 Cent can suck my dick

Tony’s words on 50 Cent — Game feud:

I remember him playing “Hate It or Love It”, I remember him paying “This is How We Do It” — I’m like you giving him this? Why you giving him this?
“Na it’s business I’m going to give it to him”.

50 also talks about Dr. Dre still producing for Game even though the two (50 and Game) were in a feud.

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