That's that crack music nigga
That real black music nigga
(That's that crack music nigga)
(That real black music nigga)

from Kanye West (Ft. Game) – Crack Music Lyrics on Rap Genius

Meaning

Crack is considered a black person’s drug and hip-hop is considered black music due to its African origins.

A few years ago (IIRC) hip-hop overtook country as the most popular genre in America, so really he’s talking about hip hop music being addictive music for everyone.

Kanye has explained that he initially didn’t want to use the n-word here. As he told Time:

Take the word ‘nigga.’ I don’t like the word, and I made an attempt to change it on this new song ‘Crack Music.’ I tried saying, ‘This is crack music, homey,‘ but it just didn’t have the same impact.

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