Going to war with the melting pot
“Melting pot” generally refers to an area that is culturally diverse — In this case likely the most well know melting pot in the world: New York City; it might also refer to a pot used to cook crack cocaine
Raekwon is saying that all of the ethnic subdivisions and/or crack dealers in New York support him in his “war” against the System
An alternate interpretation differs slightly based on the meaning of with in the line. The above takes “with” to mean together. It can also be interpreted to mean “against”. That is, Rae is going to war against the crack dealers and/or America itself.
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