Violent J discussed this song during a 2011 interview with The A.V. Club:

My brother told me that people use God’s name for evil purposes, like a guy on late-night cable TV with fat nugget rings telling you to send your money to him. My brother told me that when he was in the army, he went to this church with this girlfriend of his. He said the preacher had fucking nugget rings, and he was up there telling everyone to bring their belongings, and they were bringing all their shit and putting it on the stage. And they were bringing watches and rings and shit, and throwing them up on stage, and he was saying, “Give it all to God,” and my brother told me he saw on TV this lady said that she died and God took her on a tour through hell. In the devil’s stomach, the hottest place in hell, are people who do that, people that use God to gain money, to gain evil. Those are the people who burn the hardest.

That’s always been fucking crazy to me. So that’s what “Hellalujah” is about, because for a lot of old people, that’s all they’ve got left, their belief in God. They’ve got these people who prey on them like vultures. They’re telling them to send their little bit of money left. They’re on fixed incomes and shit. They tell them to send their money, and pure fucking craziness, and there’s nobody even stopping them. These old people, they don’t have anybody left. This ain’t like in Japan where old people are looked up upon and treated with respect. Here, nobody wants to hear an old person’s stories. They just want to fucking hawk on them and get them out of the way. Fucking old folks’ home, nobody even goes up there and visits anybody. People are just like, “Ahh, get out of the way.” It’s really fucked up. So a lot of old people don’t have nobody. So what is that person going to do? They’re going to believe in God. They’re wondering what’s next. That’s why so many old people are religious. They can’t help but think, “What’s next? I hope there’s a God.” They start getting religious. Like people on death row, they all start getting religious because they’re faced with what’s next, and they want to believe there’s something next. So you take somebody like that and some fucking crooked preacher who’s up there getting paid off old people, and fucking hookers and shit, and doing all that shit off their money, and buying a big-ass white Cadillac with a mink robe off old people sending their money into the church, you know? That’s fucked up. That’s what “Hellalujah” is about.

Shaggy 2 Dope discussed this song during a Patreon livestream on February 15, 2021:

We had a hard time even recording that song, because, fuckin', the shit was so god damn funny, the skits in that song… The cool part about that is, that’s such a fuckin' serious hardcore raw-ass song, then it breaks into the fuckin' little skits, and they’re so god damn funny, dog. It’s ridiculous… What a great-ass fuckin' song…

We probably got the idea to do “Hellalujah” from Esham records, you know what I’m saying? He has an old song on Judgement Day called “Sell Me Yo Soul,” and it’s about, like, crooked preachers. So I’m sure that’s probably a lot of inspiration of where we got the concept from, but it’s just a fuckin' great song. I’m still real proud of fuckin' “Hellalujah,” man…