With this kind of lyrical prowess they come up with in their verses, can’t nobody say that rap doesn’t need the “BAD and EVIL” regime. They are the regime this GAME needs to stay alive
Royce compares himself and Eminem to the Detroit (their hometown) Pistons of the NBA, who during the 80s were known as “The Bad Boys” because of their physical style of play. Isaiah Thomas was their star player
Isaiah is also a term used to describe the perfect form of a man (physically, mentally and all), Em' and Royce are the game’s Isaiah
Isaiah was also a prophet in the 8th-century. He and Em' are again the game’s Isaiah. This goes with the religion theme of this verse
These last two interpretations are not likely intended by Royce but are interesting nonetheless
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