The medication Marvin takes is a getaway drug; he needs it to leave from the hard, sinful, terrible world whenever he can.

The pain, awful pain.

Marvin’s vocals here crescendo sharply, mimicking the intensity of the pain he feels from withdrawal when he’s without the drugs he relies on to take him away from the cold world he and black America live in.

Charlie Sheen is another infamous user of cocaine. In multiple interviews the celebrity claimed he had tiger blood and Adonis DNA among other “qualities”.

P plays on the tiger blood and claims he has elephant blood, of course referring to the hugeness and strength of an elephant.
http://www.youtube.com/watch?feature=player_detailpage&v=OKM0cERkXJQ#t=159s

All the cocaine P is sniffing is making his body temperature go crazy, becoming cold blooded for a short period of time.

“Cold blooded” and “hell of a drug” are both also references to musician Rick James. “Cold Blooded” is a well-known song by James and “cocaine is a hell of a drug” is a phrase he coined, famously used by Dave Chappelle on The Chappelle Show.

http://www.youtube.com/watch?feature=player_embedded&v=wDoIM1dRzGo

“Tommy’s boy” is a play on the label Tommy Boy, which had all four members of Gravediggaz signed at one point. Every member was dropped by the label other than Prince Paul who “moved on”. This question and the gun shot allude that the Gravediggaz killed “Tommy’s boy” because they were unhappy with the way they got treated.

Wu-Tang Clan member GZA would do the same to Tommy Boy on his song “Labels” the following year:

Gravediggaz got lots of critique and labels didn’t want to sign them because their sound was “different” or “not what they were looking for”.

In an interview with Complex Prince Paul told a little about the label problems they had.

Jive was interested for two seconds, but one of the guys over there was like, ‘Oh, Paul? He’s old. He’s played out.’ Same thing. Getting dissed. All them dudes are old, they had records before. Why sign them?

Def Jam, obviously not, since Russell wasn’t feeling me at the time.

Tommy Boy was like, ‘Nah…’ And it was a shame, this thing I put all this effort into, the thing I wanted to show the world wasn’t working.

We had a meeting with Eazy-E. He wanted to sign us to Ruthless. I had a meeting with him and Jerry Heller in California. And I remember Eazy was like, ‘Gravediggaz—I like this. I like the demo.’ But that deal was wack! I’d rather have no deal than sign that deal.

A potter’s field is an area where unidentified or people who can’t afford an actual grave get buried. The term originates from Matthew 27:3-8.

3 – Then Judas, which had betrayed him, when he saw that he was condemned, repented himself, and brought again the thirty pieces of silver to the chief priests and elders
4 – Saying, I have sinned in that I have betrayed the innocent blood. And they said, What is that to us? see thou to that
5 – And he cast down the pieces of silver in the temple, and departed, and went and hanged himself
6 – And the chief priests took the silver pieces, and said, It is not lawful for to put them into the treasury, because it is the price of blood
7 – And they took counsel, and bought with them the potter’s field, to bury strangers in
8 – Wherefore that field was called, The field of blood, unto this day

According to the Holy Bible, Genesis 28 to be specific, Jacob’s ladder is that entrance to heaven. Here, Frukwan prepares to stab you up on the stairway to heaven, sending you to hell.

Genesis 28:11: And he lighted upon a certain place, and tarried there all night, because the sun was set; and he took of the stones of that place, and put them for his pillows, and lay down in that place to sleep.
Genesis 28:12: And he dreamed, and behold a ladder set up on the earth, and the top of it reached to heaven: and behold the angels of God ascending and descending on it.
- Genesis 28 (King James translation)

In the music video you can also see what appears to be a man sitting down and his head shaking impossibly fast, almost as if the video were glitching. This is a reference to the cult 90’s movie Jacob’s Ladder in which the protagonist see’s demons who’s faceless heads move rapidly in the same fashion.