Just as Frank had attempted to compensate for his emotional numbness using Viagra, he extends the idea to autotune. Modern corrections (“pitch corrected”) fail again and his voice still sounds “computed,” lacking any depth. Essentially science and technology can’t help his very human emotions.
This is in contrast to Ruben Studdard, who actually IS a computer…yet sings with tremendous emotion:

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Frank was trying to be someone he wasn’t. His “emotions” were dictated by what he thought the world wanted to see. They were computed (fake) rather than natural.