Monica Lewinsky is the infamous woman Bill Clinton admitted to having an “improper relationship” with.
DatPiff.com is a mixtape website that a lot of unsigned rappers use to build their buzz up. Everything there is free. On the first day he released his Best in the Burbs tape it got so many hits it crashed the server, the first time that had happened.
The beginning of the song is the “Mommy” skit from The Slim Shady EP.
He also tells parents just keep your ears near the radio because he will continue to put out hits that receive airplay.
Eminem doesn’t want to be a politician, but for this verse which is about a minute, he will try to impact kids as much as a politician could.
Slaughter you could refer to the fact that he just signed the group Slaughterhouse to his Shady Records label. He is also critical of how frequently “rappers” end up singing with the help of Auto-Tune. He will diss you in his songs as often as T-Pain (or many others) Auto-Tune in theirs.
Also when Eminem signed him to Shady Records that was the “birth” of his career that got him started.
The first time he uses “shit [is] on” he means this beef that you just caused is about to start, and the first time he uses “pissed off” is to say he is angry. But the second time he uses each word as making a fool our of other rappers.
Also has to do with the problems drug use can cause to a developing brain, since the brain doesn’t stop fully developing until about 25. Webby was only 20 when this song came out, and claimed to be drunk since 12.
Also refers to the relation-SHIP from Em’s verse. This girl is the one ruining the relationship, so he is going break up with her (throw her off the boat), and move ahead faster.