Keisha’s sister could be referring to Dave, Kendrick’s friend who was killed in front of his own eyes. This is possible due to the characters on the album are having a common interaction in some way, and is sung about in the first verse of the song. Dave, on the other hand, could have seen her when him and his homies pulled up on a bunch of working girls.

She tries to prove her point to Kendrick once again, saying that she’s so good with her clients that there will be more people who’ll remember about her rather than remember him and GKMC.

The music itself directly contradicts her however. Her lyrics literally ‘fade away’ as she sings. Despite her insistence that she knows her fate, the fading volume highlights the bitter reality that death is universal and inescapable. No matter what she claims, the reality of death makes it all bluster.

She then motivates herself, thinking that the only important thing is making money right now, whether she dies in the process or not. Her profession has disallowed her from seeing men as human beings who have also been corrupted by the “m.A.A.d city” they live in. Rather, she sees them solely as potential sources of income.

On a broader note, it means that prostitution will go on and on; the current condition of these women will perpetuate for longer than this song will be played for. This reinforces the point that Kendrick should not talk about her on his album, there is no way that the song will make any difference and the paradigm will continue well after the song has lost in popularity.

She’s upset that Kendrick released “Keisha’s Song” as she feels like Keisha was being unfairly judged. This is also due to the fact that being a prostitute will still be her job for the foreseeable future and she’s feeling judged just like her sister.

Especially in her job, the customer is always right even if he asks her to do nasty things; she has to earn that money one way or another. Her nigga refers to both Keisha’s pimp and a usual client, who are both looking for a girl to replace her with.

The preposition “behind” is also noteworthy, as it implies that she’s being “pushed” towards a dark future—this further reinforces Kendrick’s message about the hopelessness & inevitability of boys & girls getting sucked into gang life and prostitution, respectively. Just as we saw Dave’s brother follow Dave’s path, we’re seeing Keisha’s sister walking in Keisha’s footsteps—a comment on the cyclic nature of poverty and destruction.

Loco is Spanish for crazy; when people try to mess with Jay he simply draws his .44 Magnum and shoots them instead of trying to talk to them.

Stop dreamin', I leave your body steaming

Geico is an insurance company, you get money from them when you face an accident. Hova is saying that he didn’t have success by accident but by working.