Anthony is referencing the Detroit Lions & Detroit Tigers who upon the albums release were not that successful, and looking towards anything for luck, even if it means breaking some rules.

The Tigers did see some success after this release, making it to the world series.

These lines are definitely a reference to Anne Frank. In fact it’s likely the predominant (and perhaps sole) reference. Looking back at “Ghost” we have the lines:

And she was born in a bottle-rocket, 1929 /
With wings that ringed around a socket / right between her spine

As that is one of the most explicit references to Anne Frank (1929 being her birth year), it stands to reason this is as well.

That said, as this song essentially combines the themes of all previous songs (mother, father, baby, love/lust, siblings, meeting and leaving, etc.). The Anne Frank reference, though definite, could be trivial, meaning that all previous characters and themes throughout the album are becoming interchangeable.

Mangum is known for piecing together songs with old material and themes amongst the new, similar to the amalgamation of symbols in the album’s climax. In this light, blister is perhaps another reference to Goldaline from “Oh Comely,” the 8th track of the album.

Goldaline has sacrificed herself to keep her sister alive (being a conjoined twin comes with many complications), which has left a big blister on her side where she use to live. These lines are also reminiscent of the first track of the album – “The King Of Carrot Flowers Part 1” – in which Mangum sings:

And your mom would stick a fork right into daddy’s shoulder / And dad would throw the garbage all across the floor / As we would lay and learn what each other’s bodies were for

Some interpretations offer the idea that the above lyrics refer to half siblings, which could indicate “Two Headed Boy Pt. 2” as an intertwining story about his half-brother’s theoretical sexual relationship with the now-separated twin girl. However, in Kim Cooper’s 33 1/3 book on Aeroplane, she explains that the song’s original lyrics may have bearing on the end product’s meaning:

A few months before the album was recorded, Jeff was singing Aeroplane’s final song with slightly, yet significantly, different lyrics. The changes are telling, because they suggest that this song, one of the most beautiful on the record, is part of the Anne Frank cycle. The early “Sister please” becomes the euphonious, but nonsensical, “Blister please” on the album.

“Blister,” however, in keeping with the upper section of this annotation, is a portmanteau of “brother” and “sister,” further lending credibility to the blending and mixing of symbols here in the end.