Dr. Dre and Eminem take on the roles of Batman and Robin, respectively.

Em parodies Robin’s famous statement, “Holy (insert funny word here), Batman!”, whereas Dre parodies the famous, “to the Batmobile!"—but it’s, you know, the Rapmobile, which incidentally is a yellow Lamborghini that can be seen in the music video to ”Without Me“.

The “crime” the duo are fighting are wack MCs with bad lyrics (hence “holy wack unlyrical lyrics!”)

Em also once began a very old track with:

To the Batmobile, let’s go!

and would do an intro as Batman and Robin later in his career with 50 Cent on “Gatman and Robin”.

Due to lacking a brain, Em has forgotten his name. This is also a reference to “My Name Is,” and its memorable hook:

Hi, my name is, what? My name is, who?
My name is, chka-chka Slim Shady
Hi, my name is, huh? My name is, what?
My name is, chka-chka Slim Shady

Throughout his whole career, Em has faced criticism from both parents and politicians, since they think his music is homophobic, violent and encouraging bad behavior. He has tackled this issue earlier on songs such as “White America” and “Sing for the Moment”.

We could also understand that this was specifically about Christopher Reeve’s comment, where he says he found the song “Superman” offensive. {citation needed}

Eminem, The Way I Am (book) (2008):

I went down [to Lou Pearlman’s recording studio in Orlando, in Summer 2004] with nothing, not even a concept. I had the line, “You find me offensive, I find you offensive” in my head, and I had no idea where it was going to go from there.

A reference to the title character of the movie Rain Man, who is an autistic savant. Em is mimicking the character’s frequent repetition of the word “definitely” before saying something.

Also, Em mentions K-Mart because in one scene from the movie, Rain Man starts panicking and gets obsessive with the fact that he needs his underwear from “K-Mart, 400 Oak Street, Cincinnati”. This is attributed to his autism.

Christopher Reeve was an actor who played Superman, and was paralyzed after a 1995 horse-riding accident. While Em, won’t stand for it, Reeve who physically can’t stand for it, will instead not sit for it. Also, he is saying Chri-stiff-pher Reeves, pronouncing it “stiff” as in paralyzed.

Reeve has been a common source of jokes from Em, for instance on “I’m Back” and “My 1st Single” and later on “Campaign Speech”. Em’s constant jabs at the actor, led people to belive that the two were beefing. However, Em explained the reason to why Reeve constantly was the target of his jokes on “Medicine Ball”:

Now everybody’s pissed at me, like it’s my fault
This name rhymes with so many different words, jeez
So one last time, Mr. Christopher Reeves

The jokes didn’t stop after Reeve passed away in 2004, something Em commented on in his 2009 “Rap City” freestyle:

I Need Christopher Reeves to come and lay his verse
I think he can spit it better on Medicine Ball
First off I did not even realize the guy died
So I guess them Christopher Reeves jokes ain’t gonna fly

This reflects another big pop culture incident from the period of recording Encore. In 2003, Michael Jackson, who lived at the famous Neverland Ranch, was formally charged with child molestation after accusations from 1993. Jackson was acquitted of all charges in 2005.