His rebuttal (the 3rd verse) to this message literally comes too late as she has already faded away by the time he can explain himself.

When she says she gets enough attention on her own, she’s saying it to brag (not to plead with Kendrick to not mention her in his album) about how well she’s doing for herself as a hooker – which ties in with the defiant, “don’t feel sorry for me” tone of the previous lines.

She sardonically references the first time that she was used by three men at once (or “tossed”) as an example of how she was taught how to be a woman.

She doesn’t need Kendrick to apologize for the life she was forced into. She rejects criticism from people who can’t sympathize with her plight.

This line also marks a dramatic change in Keisha’s sister’s tone as she goes from sounding weak and vulnerable to sounding angry and forceful.

Kendrick plays on the word genes, pronouncing it like jeans to connect to a “denim” of a family gene.

If she would have been a girl cut from a cloth who had love and support for her instead of being a foster kid, she’d have learned how to respect her body and how to make others do the same, especially in the household.

She feels so far gone and so embroiled in a certain way of living that it’s easier to imagine how it’d have been to live a different life rather than fix the one she’s living.

The woman Kendrick characterizes knows the rhythmic jingling sound of car keys is a signal. She knows her client has removed them from the ignition and stopped following her, an indicator for her to approach his car.

K-dot paints a picture of the harsh, unfortunate reality for many young girls who grew up where Kendrick came from and in tough cities across the country.

While most people Lamar encounters through good kid, m.A.A.d city find themselves trapped in Compton and gang life, Lamar wants to follow his dream of becoming a rapper. This would allow him to “sing about” the speaker and help him live on through music when he grows his platform.

This may be a reference to Martin Luther King’s 1963 “I Have a Dream” speech, which described his hopes for a future free of racial segregation. Lamar previously compared himself to King on earlier track “Backseat Freestyle”:

Martin had a dream
Kendrick have a dream

When gunshots are fired (or the metaphorical thunder), cats and dogs, or his friends, die. It’s a reference to the old saying “It’s raining cats and dogs”, and also demonstrates some wordplay as the TV series ‘ThunderCats’ aired during Kendrick’s youth.

It’s also a metaphor of the saying, “when it rains it pours” (meaning that trouble for Dave’s brother just seems to exponentially grow and never get better).

Notice how he distorts “When thunder comes” to sound like the previous “Dun-ta-duns”

After the lavish lifestyle ideology propelled by the music, who’s influence he was under, Kendrick is back among the cruel reality of Compton, a place where rivalry between gangs causes casualties, similar to a war. A victim of the the ongoing violence was his Uncle Tony, killed at Louis Burgers. Not only is Kendrick poor in a monetary sense, he and his crew are now pouring liquor on the curb in memory of his Uncle Tony.

Kendrick’s family have always been portrayed as supportive, but here his Uncle displays the kind of encouragement a lot of rappers and entertainers never experience; a belief in his abilities.

The shock of losing a supportive figure puts a permanent stain on that Louis Burgers, and exemplifies the deep ties that Kendrick has to his city. His “dreams of living life like rappers do” are interrupted by the pain that gang culture brings, and that pain is not eased by expensive clothing.