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Wayne shouts out Swizz Beatz, the track’s producer. Swizz had worked with Wayne previously on “Dr Carter” from Wayne’s widely acclaimed Tha Carter III album.

“I Can Transform Ya” also marked the second time Chris and Swizz worked together, following “I’ll Call Ya” from his 2007 album, Exclusive.

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What is this?

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Wayne is stating that can change a girl just by being with her. He can change her mind about love, about him, about everything. Funnily, Lil Wayne’s girl would become a “Lil Mama.”

“Hey lil' mama” is also how Chris' 2007 single “With You” opens.

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Royce (Bad) left the club to see his Evil (Eminem) twin who just crashed in front of the club…

Eminem later sampled this line on the hook of his song “Evil Twin” off the Marshall Mathers LP 2.

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The killers are now celebrating, stealing the dead man’s chain and selling it, going to a jazz block party downtown and relaxing.

Second Line is a parade specifically in New Orleans.

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Wayne shows that professional criminals take pains to erase the identities of those who they kill.

Using gloves, no number plates, covering their face, and escaping soon after is how a lot of killings go down in NO.

This could also be that in New Orleans, death happens so often, that as soon as you’re murdered, you aren’t remembered as yourself, but you just become a statistic, erased from history.

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What is this?

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The minute Weezy sees a crowd, he automatically goes into performance mode for them.
His performances have been know to be very loud and energetic.
http://youtu.be/uiVr1NNRrDw

This is a reference to the show In Living Color, which is a live skit comedy show similar to SNL.

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Optimus Prime is the leader of the autobots in the Transformers series, and is mostly known to change from a robot form to a Freightliner Cab-over-engine Class 8 truck.

Here, Wayne wants to transform his girl as easily as Optimus would.

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This is a gun reference to banana clips in guns.
Also a play on words ‘bone thugging’, since Bone-Thugs n Harmony are from Cleveland, Ohio.

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