- Set It Off by Add-2
- Sharp by Wale (Ft. Kingpin Slim & Torae)
- Sharp by The 3rd Kind
- Shining by Laws
- Shinin' Star by Terrace Martin
- Short Story by Median
- Shorty Left by 9th Wonder & Buckshot (Ft. Rapsody)
- Shorty on the Lookout by Little Brother (Ft. Median)
- Silly by David Banner & 9th Wonder (Ft. Erykah Badu) prod. by Chris "THX" Goodman & David Banner
- Silly Girl by Murs (Ft. Joe Scudda)
- Sin by Murs, 9th Wonder & The Soul Council prod. by The Soul Council
- Sincere by The Foreign Exchange (Ft. YahZarah) prod. by Nicolay
- Sincerely Yours by Little Brother
- Sinners by Little Brother
- Skills that Kill by Tha Arkhitekt
- Slippin by Psyonik
- Slippin by 9th Wonder & Buckshot
- Slow it Down by Little Brother (Ft. Darien Brockington)
- Smoke Pains by Enyukay
- Smokey Robinson's L by Charles Hamilton