All that holy water shit is nothing short of nonsense
Not denying Christ, I'm just denying niggas options
Cus prayer never moved my Grandmama out of Compton
I prayed for my cousin, but them niggas still shot him

from Vince Staples – Versace Rap Lyrics on Rap Genius

Meaning

The flash and hype behind religion is all bogus, Vince isn’t saying Jesus wasn’t knowledgable, wise, or chosen. He is just more concerned that his teachings aren’t going to help him out of the troubles he faces in his life. So he doesn’t need to pay attention to someone who isn’t helping him. The only time he did pray, he was let down.

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