Walk out the door and they scream it's alive

from Kendrick Lamar – Bitch, Don't Kill My Vibe Lyrics on Rap Genius

Meaning

The line “it’s alive” could be a reference to the movie “Frankenstein”, in which the mad scientist has created a monster and yells “It’s Alive!”. Perhaps Kendrick is portraying himself as a monster (in a good way).

After fans leave Kendrick’s concert or hearing his music for the first time (after waiting in a long line for him like it’s the 1st or 15th), they scream “it’s alive”, because their faith has been restored that hip-hop still lives with Kendrick Lamar

Kendrick could also be referring to the extent of his struggle to get here: he’s saying that he’s been through so much that people can’t grasp the fact that Kendrick Lamar is still in the game.

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