When it comes to that weight I don't struggle, I just lift

from Lil Wayne – Money on My Mind Lyrics on Rap Genius

“Weight” means drugs, and Lil Wayne doesn’t have a hard time selling a lot of drugs (someone might “struggle” when lifting weights at the gym)

Also might be a reference to the fact that he settles disagreements by simply “lifting” his gun and shooting, so he doesn’t have to “struggle” with putting up with disagreeable people / lifting weights at the gym to get strong

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