And, yes, these gold diggers trying to get at my sperm
Well, I'm not a 49ers fan, in case you haven't heard

from Childish Gambino (Ft. DC Pierson) – 49ers (Orange Shirt) Lyrics on Rap Genius

All of these gold digging girls (49ers) are trying to have sex with CG to get his money. However, he’s not a fan of gold diggers and won’t fuck with them.

He’s making a reference to the California Gold Rush, where everyone rushed to Cali to dig for gold. These people were called “49ers,” thus the name of the San Francisco football team and this song. When CG says he’s not a fan of 49ers, he doesn’t necessarily mean the team. He’s sick of bitches getting on his dick for the money and the fame and not for him as a person.

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