Thirsty chicks trying to give it, I don't want it
You been in more laps than the Indy 500
from DJ Drama (Ft. Future, Ludacris, T.I. & Young Jeezy) – We in This Bitch Lyrics on Rap Genius
Meaning
Desperate chicks are trying to get with Ludacris in the club and he doesn’t want them.
The Indy 500 is a 200 lap, 500 mile race car event that occurs annually over Memorial weekend at Indianapolis Motor Speedway in Speedway, Indiana. Luda is saying these desperate women are hopping from man to man in the club and sitting on their laps flirting.
Thirsty chicks just after some free champagne and money.

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