So bitch, let's fuck so I can smoke again
I gotta smoke again,

from Chance The Rapper (Ft. Ab-Soul) – Smoke Again Lyrics on Rap Genius

Meaning

Nothing better than the drug and sex combination, (ohh, sorry, blank and blank). The title is probably enough for you to know what this one’s going to be about, but the man himself explained it on Sway in the Morning:

This smoke again song is about, after you’ve smoked once, umm…smoking again! IGH! IGH! IGH! IGH!

http://youtu.be/fmHlxpnYlGk?t=6m13s

To help improve the meaning of these lyrics, visit “Smoke Again” by Chance The Rapper (Ft. Ab-Soul) Lyrics and leave a comment on the lyrics box